Wegovy
The semaglutide brand built specifically for weight loss. Higher doses than Ozempic, with the strongest weight-loss data of any approved GLP-1 medication.
Wegovy is a higher-dose version of semaglutide (the same drug in Ozempic) designed specifically for weight management. In clinical trials, it helped people lose an average of 15–17% of their body weight — more than any previously approved weight-loss medication.
Good for you if: You have a BMI of 30+ (or 27+ with weight-related conditions like high blood pressure or type 2 diabetes) and your doctor recommends medical support for weight management.
Dive deeper into the researchCommon side effects
- Nausea in 40–50% of users — most common during the titration phase
- Significant muscle loss (25–40% of weight lost) without exercise countermeasures
- Weight regain is common if you stop — about two-thirds comes back within a year
What does Wegovy do?
Wegovy works exactly like Ozempic — it mimics a gut hormone called GLP-1 that regulates appetite and blood sugar. The difference is the dose: Wegovy goes up to 2.4 mg/week (vs Ozempic's 2 mg maximum), and it's specifically approved and studied for weight loss.
It reduces your appetite, makes you feel full sooner, and slows digestion. You naturally eat less without the constant willpower battle. Over 68 weeks in the STEP 1 trial, people lost an average of 15–17% of their body weight.
Who is it for?
- Adults with BMI ≥30 (obesity)
- Adults with BMI ≥27 plus at least one weight-related condition (type 2 diabetes, high blood pressure, high cholesterol, sleep apnoea)
- People who haven't achieved meaningful weight loss with diet and exercise alone
Wegovy is not a cosmetic tool. It's a medical intervention for people whose weight is causing or worsening health problems. Your doctor will assess whether it's appropriate for you.
How it's taken
Month 1: 0.25 mg/week → Month 2: 0.5 mg → Month 3: 1.0 mg → Month 4: 1.7 mg → Month 5+: 2.4 mg/week
Inject once weekly in your stomach, thigh, or upper arm. Same day each week. If nausea is significant at any dose, stay there for an extra 4 weeks.
How long to stay on it: Wegovy is designed for long-term use. Most clinical trials ran 68+ weeks. Stopping the medication typically leads to weight regain, so your doctor will discuss an ongoing plan.
Availability in India
Wegovy has limited availability in India — it's not as widely stocked as Ozempic. Some specialty obesity clinics and metropolitan pharmacies can source it. Many Indian doctors use Ozempic off-label for weight management instead, as it contains the same drug at a slightly lower maximum dose.
Expected cost: ₹8,000–₹15,000 per month depending on dose and sourcing.
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Get early accessFrequently Asked Questions
How much weight can you lose on Wegovy?
In the STEP 1 trial, people on Wegovy lost an average of 15–17% of their body weight over 68 weeks. For someone weighing 100 kg, that's about 15–17 kg. Some people lose more, some less — results depend on diet, exercise, and individual biology.
What is the difference between Wegovy and Ozempic?
Both contain the same active ingredient — semaglutide. Wegovy goes up to 2.4 mg/week and is specifically approved for weight management. Ozempic maxes out at 2 mg/week and is approved for type 2 diabetes. The drug itself is identical.
Is Wegovy available in India?
Wegovy has limited availability in India. Some specialty obesity clinics can source it, but it is not as widely stocked as Ozempic. Many Indian doctors prescribe Ozempic off-label for weight management instead. Cost is approximately ₹8,000–₹15,000 per month.
Do you regain weight after stopping Wegovy?
Yes, most people regain about two-thirds of lost weight within 12 months of stopping. The appetite-suppressing effect stops when the drug stops. Building sustainable habits while on the medication is critical for long-term success.
How it works in your body
Semaglutide (Wegovy's active ingredient) binds to GLP-1 receptors in your brain's appetite centres, reducing hunger and food reward. It also slows gastric emptying and improves insulin sensitivity. The 2.4 mg dose provides stronger appetite suppression than the lower doses used in Ozempic.
Clinical trial data
- STEP 1: 14.9% weight loss vs 2.4% placebo over 68 weeks in adults with obesity
- STEP 2: 9.6% weight loss in adults with type 2 diabetes and obesity
- STEP 3: Combined with intensive behavioural therapy — 16% weight loss
- STEP 5: Sustained weight loss over 2 years of continuous treatment
- SELECT: 20% reduction in major cardiovascular events in people with obesity
Biomarker monitoring
While on Wegovy, track these markers before starting and every 3–6 months:
- Body composition (DEXA scan) — track fat vs lean mass changes
- HbA1c and fasting glucose — metabolic improvement
- Lipid panel (ApoB, triglycerides, LDL, HDL)
- Liver enzymes — fatty liver often improves
- Vitamin B12, iron, ferritin — reduced food intake can cause deficiencies
Side effects & safety
Wegovy's side effects are identical to Ozempic's — same drug, same profile. The higher dose may mean slightly more GI side effects during titration.
- Nausea (40–50%) — most common, usually fades after 4–8 weeks at each dose. Slow titration is key.
- Vomiting (15–25%), diarrhoea (15–30%), constipation (10–20%)
- Muscle loss — 25–40% of weight lost is lean mass without countermeasures. Resistance training and high protein intake are non-negotiable.
- Hair loss — telogen effluvium in 3–6% of users from rapid weight loss
- Facial volume loss ("Ozempic face") — slower weight loss helps
- Pancreatitis — rare but serious. Severe abdominal pain radiating to the back = emergency.
- Gallbladder disease — increased gallstone risk with rapid weight loss
- Thyroid C-cell tumours — contraindicated with personal/family history of MTC or MEN 2
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